The object of this proposal is to convene a third International Conference on Proteins of Iron Storage and Transport to be held April 11-14, 1977, at Arden House, Harriman, New York. Approximately 100 scientists and clinicians from laboratories throughout the world will be invited to present their current investigations in the field of iron storage and transport in a conference format designed to allow maximum communication of ideas and the bridging of various disciplines of basic science and clinical medicine. A tentative outline of the program of this conference includes an opening plenary lecture on th solution chemistry of ion followed by a series of 10 to 20 minute papers and informal workshop sessions under the following major headings: 1. Newer Insights into the Structure of Transferrin; 2. Interaction of Transferrin with Teticulocytes and other Iron-Seeking Cells; 3. Structure of the Isoferritins; 4. Functional Role of the Ferritins; 5. Iron-Proteins and the Regulation of Iron Absorption; and 6. Iron-Binding Proteins and Disorders of Iron Metabolism.